Depression, hormonal status and erectile dysfunction in the aging male: results from a community study in Malaysia

  • WY Low
  • EM Khoo
  • HM Tan
  • FL Hew
  • SH Teoh

Abstract

This paper examined the association between depression,erectile dysfunction and hormonal status among aging menand factors predictive of their erectile function, based on acommunity-based survey involving 351 men living in the KlangValley, Selangor. The International Index of Erectile Function(IIEF-5) was used to assess the presence of erectiledysfunction and its severity while the 15-item GeriatricDepression Scale (GDS-15) was used as a screeninginstrument for depression.14.5% of men were found to have mild/moderate depressionwhile 11% had severe depression. Men with ED havesignificantly higher GDS scores, higher levels of SHBG* andhigher proportion of abnormal hormone levels (PSA*, SHBG,LH*, total testosterone, free testosterone, bio-availabletestosterone, prolactin and IGF-1*), compared to men withoutED. ED was associated with depressive symptoms and aging,however, no association between total testosterone anddepression. Age and depression explained 18.2% of thevariance in erectile function. Total testosterone, LH, freetestosterone and SHBG did not predict erectile function scores.In the management of ED or depression, cardiovasculardisease should also be screened for. These conditions areoften missed if either condition is dealt with in isolation. (copied from article)
Published
2012-03-31
How to Cite
LowW., KhooE., TanH., HewF., & TeohS. (2012). Depression, hormonal status and erectile dysfunction in the aging male: results from a community study in Malaysia. Malaysian Family Physician, 2(1), 1. Retrieved from https://www.e-mfp.org/ojs3/index.php/MFP/article/view/129
Section
Original Articles