Is there a role for aspirin in primary prevention of ischemic heart disease in hypertensive patients?

  • Keng Yin Loh
  • Soo Chin Chan

Abstract

Madam X, a 60 year old housewife who has chronic essential hypertension for the past 10 years on oral antihypertensive treatment. Her blood pressure is well controlled 130/80 mmHg. She is a non smoker and non diabetic. Her body mass index (BMI) is 28.5 kg/m2. She has no end organ target damage. She asks if she need to take aspirin, as she heard from her friends that aspirin can prevent ischaemic heart disease.

Question: In a patient with essential hypertension but without other medical disorders or complications, should aspirin be prescribed to prevent coronary artery disease? (copied from article)

References

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Hayden M, Pignone M, Phillips C, Mulrow C. Aspirin for the primary prevention of cardiovascular events: summary of the evidence. Ann Int Med. 2002 Jan 15;136(2):161-72.

He J, Whelton PK, Vu B, Klag MJ. Aspirin and risk of hemorrhagic stroke: a meta-analysis of randomized controlled trials. JAMA. 1998 Dec 9;280(22):1930-5.

Sanmuganathan PS, Ghahramani P, Jackson PR, Wallis EJ, Ramsay LE. Aspirin for primary prevention of coronary heart disease: Safety and absolute benefit related to coronary risk derived from meta-analysis of randomised trials. Heart. 2001 Mar;85(3):265-71.

Published
2006-03-31
How to Cite
LohK. Y., & ChanS. C. (2006). Is there a role for aspirin in primary prevention of ischemic heart disease in hypertensive patients?. Malaysian Family Physician, 1(1), 1. Retrieved from https://www.e-mfp.org/ojs3/index.php/MFP/article/view/232
Section
Original Articles