Recurrent stroke: what have we learnt?
AbstractStroke is the third leading cause of death, a major cause of disability in adults, and is frequently more disabling than fatal.With a decline in mortality from initial cerebral infarction and an increase in the life expectancy of the population, the number of patients with recurrent stroke and ensuing cardiovascular events will become greater. Thus it is important to find out those patients athigh risk of stroke recurrence. This case report illustrates the process of recurrent stroke and the resulting disabilities andmorbidities in a 42-year- old man. The role of integrated stroke rehabilitation programme is described.
Benavente O, Hart RG. Stroke: Part II. Management of acute ischemic Stroke. Am Fam Physician. 1999;59(10):2475-82.
Ezekowitz JA, Straus SE, Majumdar SR, McAlister FA. Stroke: Strategies for primary prevention. Am Fam Physician. 2003;68(12):2379-86.
Benavente O, Hart RG. Stroke: Part I. A clinical update on prevention. Am Fam Physician. 1999;59(9):2475-86.
Carlberg B, Samuelsson O, Lindholm LH. Atenolol in hypertension: is it a wise choice? Lancet. 2004: 364:1684-9.
Lindholm LH, Carlberg B, Samuelsson O. Should beta-blockers remain first choice in the treatment of primary hypertension? A meta-analysis. Lancet. 2005;366:1545-5.
PROGRESS Collaborative Group. Randomised trial of a perindoprilbased blood pressure lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack. Lancet. 2001;358:1033-41.
Dahlof B, Devereux RB, Kjeldsen SE, et al. Cardiovascular morbidity and mortality in the Losartan Intervention for endpoint reduction in hypertension study (LIFE). A randomized Trial against atenolol. Lancet. 2002;359:995-1003.
Yusuf S, Sleight P, Pogue J, et al. Effects of an ACEI, ramipril, on CV events in high-risk patients. The Heart Outcome Prevention Evaluation Trial. N Engl J Med. 2000; 342:145-53.
Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet. 2002;360:7-22.
The Scandinavian Simvastatin survival study Group. Randomized trial of cholestrol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study(4S). Lancet. 1994;344:1383-9.
Collaborative overview of RCT of antiplatelet therapy. Antiplatelet trialists’ collaboration. BMJ. 1994;308:81-106.
Mohd Rani J (Chair). Consensus statement on the management of ischaemic stroke. Ministry of Health Malaysia, Academy of Medicine Malaysia; 2000.
Hass WK, Easton JD, Adams HP, et al. A randomized trial comparing ticlopidine hydrochloride with aspirin for the prevention of stroke in high-risk patients. Ticlopidine Aspirin Stroke Study Group. N Engl J Med. 1989;321(8):501-7.
A randomized, blinded, trial of clopidogrel versus aspirin in patients at high risk of ischemic events. CAPRIE steering committee. Lancet. 1996;348: 1329-39.
Hankey GJ, Sudlow CLM, Dunbabin DW. Thienopyridine derivatives (ticlopidine, clopidogrel) versus aspirin for preventing stroke and other serious vascular events in high vascular risk patients. Cochrane Database Syst Rev. 2000, Issue 1. Art. No.: CD001246. DOI: 10.1002/14651858.CD001246.
Diener HC, Cunha L, Forbes C. European Stroke Prevention Study 2. Dipyridamole and acetyl salicylic acid in the secondary prevention stroke. J Neurol Sci. 1996;143(1-2):1-13.
De Schryver ELLM, Algra A, Van Gijin J. Dipyridamole for preventing stroke and other vascular events in patients with vascular disease. Cochrane Database Syst Rev. 2007, Issue 3. Art. No.: CD001820. DOI: 10.1002/14651858.CD001820.pub3.
Hankey GJ, Jamrozik K, Broadhurst RJ et al. Long-term risk of first recurrent stroke in the Perth Community Stroke Study. Stroke. 1999;29(12):2491-500.
Cina CS, Clase CM, Haynes RB. Carotid endarterectomy for symptomatic carotid stenosis. Cochrane Database Syst Rev. 1999, Issue 3. Art. No.: CD001081. DOI: 10.1002/14651858.CD001081.
Cruz-Flores S, Diamond AL. Angioplasty for intracranial artery stenosis. Cochrane Database Syst Rev. 2006, Issue 3. Art. No.: CD004133. DOI: 10.1002/14651858.CD004133.pub2.