Contact lens related corneal ulcer

  • KY Loh
  • Agarwal P
Keywords: Contact lens, corneal ulcer, diagnosis, prevention

Abstract

A corneal ulcer caused by infection is one of the major causes of blindness worldwide. One of the recent health concerns isthe increasing incidence of corneal ulcers associated with contact lens user especially if the users fail to follow specificinstruction in using their contact lenses. Risk factors associated with increased risk of contact lens related corneal ulcers are:overnight wear, long duration of continuous wear, lower socio-economic classes, smoking, dry eye and poor hygiene. Thepresenting symptoms of contact lens related corneal ulcers include eye discomfort, foreign body sensation and lacrimation.More serious symptoms are redness (especially circum-corneal injection), severe pain, photophobia, eye discharge andblurring of vision. The diagnosis is established by a thorough slit lamp microscopic examination with fluorescein staining andcorneal scraping for Gram stain and culture of the infective organism. Delay in diagnosing and treatment can cause permanentblindness, therefore an early referral to ophthalmologist and commencing of antimicrobial therapy can prevent visual loss.

References

Bar JT. History and development of contact lens. In: Bennett ES, Weisman BA. Clinical contact lens practice. Lippincott Williams & Wilkins; 2004. p. 1-5

Liesegang TJ. Contact lens-related microbial keratitis: Part 1: Epidemiology. Cornea. 1997;16(2):125-31.

Reddy SC, Tajunisah I. Contact lens-related infectious keratitis in Malaysia. Ann Ophthalmol (Skokie). 2008;40(1):39-44.

Hooi SH, Hooi ST. Culture-proven bacterial keratitis in a Malaysian general hospital. Med J Malaysia. 2005;60(5):614-23.

Stapleton F. Contact lens-related microbial keratitis: what can epidemiologic studies tell us? Eye Contact Lens. 2003;29 (1 Suppl):S85-9.

Stapleton F, Keay L, Edwards K, et al. The incidence of contact lens-related microbial keratitis in Australia. Ophthalmology. 2008;115(10):1655-62.

Behlau I, Gilmore MS. Microbial biofilms in ophthalmology and infectious disease. Arch Opthalmol, 2008;126(11):1572-81.

Toutain-Kidd CM, Kadivar SC, Bramante CT, et al. Polysorbate 80 inhibition of biofilm formation of Pseudomonas aeruginosa and its cleavage by the secreted lipase LipA. Antimicrob Agents Chemother. 2009;53(1):136-45.

Guillon M, Maissa C. Contact lens wear affects tear film evaporation. Eye Contact Lens. 2008;34(6):326-30.

Dart JK, Radford CF, Minassian D, et al. Risk factors for microbial keratitis with contemporary contact lenses: a case-control study. Ophthalmology. 2008;115(10):1647-54.

Efron N, Morgan PB. Rethinking contact lens associated keratitis. Clin Exp Optom. 2006;89(5):280-98.

Donzis PB. Corneal ulcers from contact lenses during travel to remote areas. N Engl J Med. 1998;338(22):1629-30.

Sankaridurg PR, Sweeney DF, Sharma S, et al. Adverse events with extended wear of disposable hydrogels: results for the first 13 months of lens wear. Ophthalmology. 1999;106(9):1671-80.

Green M, Apel A, Stapleton F. Risk factors and causative organisms in microbial keratitis. Cornea. 2008;27(1):22-7.

Jhanji V, Beltz J, Vajpayee RB. Contact lens-related acanthamoeba keratitis in a patient with chronic fatigue syndrome. Eye Contact Lens. 2008;34(6):335-6.

Gangopadhyay N, Daniell M, Weih L, et al. Fluoroquinolone and fortified antibiotics for treating bacterial corneal ulcers. Br J Ophthalmol. 2000;84(4):378-84.

Published
2012-03-31
How to Cite
LohK., & PA. (2012). Contact lens related corneal ulcer. Malaysian Family Physician, 5(1), 3. Retrieved from https://www.e-mfp.org/ojs3/index.php/MFP/article/view/90
Section
Original Articles